GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | EPDR1 | chr7:37960163-37991539:+ | 0.34 | 7.6 | 1.58E-13 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | GGT5 | chr22:24615623-24641110:- | 0.27 | 6.21 | 1.17E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | LRRC42 | chr1:54412037-54433839:+ | -0.23 | -6.03 | 3.21E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | MALL | chr2:110841452-110874143:- | 0.29 | 5.91 | 6.59E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.77 | 3.05E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | PLCE1 | chr10:95753746-96088146:+ | 0.26 | 6.08 | 2.53E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | SEMA5B | chr3:122628043-122747452:- | -0.31 | -5.9 | 6.83E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7032019 | chr9:100548144 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.18 | 1.35E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7032019 | chr9:100548144 | CLDN2 | chrX:106143394-106174091:+ | 0.26 | 6.06 | 2.81E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7032019 | chr9:100548144 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.86 | 2.11E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7032019 | chr9:100548144 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7.11 | 4.19E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7032019 | chr9:100548144 | GGT5 | chr22:24615623-24641110:- | 0.26 | 5.94 | 5.54E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7032019 | chr9:100548144 | LRRC42 | chr1:54412037-54433839:+ | -0.23 | -6.05 | 2.94E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7032019 | chr9:100548144 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.83 | 2.07E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7032019 | chr9:100548144 | PLCE1 | chr10:95753746-96088146:+ | 0.27 | 6.13 | 1.81E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |